![]() IV Loading dose is 0.02 to 0.04 mg/kg (maximum single dose 2 mg) Maintenance dose is 0.02 to 0.06 mg/kg every 2 to 6 hours as needed or 0.01 to 0.1 mg/kg per hour with a maximum dosing of less than 10 mg per hour.Īlcohol Withdrawal Delirium (off-label use) ![]() Īdministered IV, the dose is 0.1 mg/kg (maximum dose 4 mg), at a maximum rate of 2 mg per minute may repeat in 5 to 10 minutes Note: Must dilute dose with 1:1 saline.Īgitation in the Intensive Care Unit (ICU) Patient (off-label use) In patients older than 50 years of age, the maximum dosage is 2 mg. ![]() If administered IV, the dose is 0.044 mg/kg administered 15 to 20 minutes before surgery (maximum dose 4 mg). If given IM, the dose is 0.05 mg/kg administered 2 hours before surgery (maximum dose 4 mg). In patients less than 65 years of age, the dose is 0.5 to 2 mg orally at bedtime, and in patients over 65 years of age, the dose is reduced to 0.5 to 1 mg at bedtime. The initial starting dose is 2 mg to 3 mg orally, can repeat dose 2 to 3 times per day the maximum dosage is 10 mg per day. Lorazepam has an 85% bioavailability when taken by mouth and is metabolized in the liver by glucuronidation using the CYP450 enzymes, and has a half-life of 14 hours. Lorazepam immediate-release tablet reaches its peak plasma time in 2 hours if administered orally. The onset of its action is 1 to 3 minutes if administered IV and 15 to 30 minutes if administered IM. It can be administered via intravenous(IV) or intramuscular(IM) injection (2 mg/mL solution, and 4 mg/mL solution). This series includes audio files of the highest quality, is adaptable to the individual needs of your students, and features appropriate sequencing of activities to help students progress from sound to sight.Lorazepam can be administered orally (0.5 mg tablet, 1 mg tablet, 2 mg tablet, oral concentrate solution 2 mg/mL, 1 mg extended-release capsule, 2 mg extended-release capsule, and 3 mg extended-release capsule).
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